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Acetylcholine regulates

  • Memory formation1

Acetylcholine is very similar in structure to nicotine and binds to the same receptors. The high comorbidity of ADHD and smoking indicates a connection.2

The significance of acetylcholine in relation to ADHD is still largely unexplored.

A meta-analysis study reported increased choline levels in the blood of ADHD sufferers3

  • PFC
  • Striatum
  • Anterior cingulate cortex.

Choline is a precursor of acetylcholine as well as phosphatidyl-choline and sphingomyelin.