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Aripiprazole for ADHD


Aripiprazole for ADHD

A systematic review examined the effect of aripiprazole on ADHD. Only 2 RCTs (randomized controlled trials) were found.1 No controlled study found an efficacy of aripiprazole on ADHD symptoms. Efficacy of aripiprazole on ADHD was only found in non-controlled studies. There was a very high rate of side effects such as

  • Weight gain
  • Sedation
  • Headaches reported.

One study compared the effects of aripiprazole and risperidone in children with ADHD and comorbid ASD.
Both drugs showed a comparable improvement in ADHD symptoms without serious side effects; aripiprazole showed a reduction in prolactin levels.2

One study found a positive effect of a combination therapy of aripiprazole and methylphenidate in children with comorbid DMDD and ADHD. Increased side effects were not found.3