Amitriptyline for ADHD
Amitriptyline is a tricyclic antidepressant
- Serotonergic, as a serotonin reuptake inhibitor, with this effect predominating1
- Weaker also noradrenergic
Metabolite of amitryptiline is nortriptyline, which inhibits norepinephrine reuptake. See ⇒ Nortriptyline in ADHD.
Amitryptiline has sleep-inducing and anxiolytic effects. Like trimipramine, it does not impair REM sleep.