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Amitriptyline for ADHD


Amitriptyline for ADHD

Amitriptyline is a tricyclic antidepressant

  • Serotonergic, as a serotonin reuptake inhibitor, with this effect predominating1
  • Weaker also noradrenergic

Metabolite of amitryptiline is nortriptyline, which inhibits norepinephrine reuptake. See Nortriptyline in ADHD.

Amitryptiline has sleep-inducing and anxiolytic effects. Like trimipramine, it does not impair REM sleep.

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