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Amitriptyline for ADHD


Amitriptyline for ADHD

Amitriptyline is a tricyclic antidepressant

  • Serotonergic, as a serotonin reuptake inhibitor, whereby this effect predominates1
  • Weaker also noradrenergic

The metabolite of amitryptiline is nortriptyline, which inhibits the reuptake of noradrenaline. For more information, see Nortriptyline in AD(H)S.

Amitryptiline has a sleep-promoting and anxiolytic effect. Like trimipramine, it does not impair REM sleep.

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