PDC-1421 for ADHD
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PDC-1421
Extract from Radix Polygalae (Polygala tenuifolia Willd.; Siberian cruciferous root)
Noradrenaline reuptake inhibitors
Antidepressant effect
A Phase 2 study with PDC-1421 in 6 adults over 28 days showed therapeutic potential for the treatment of ADHD.12
McBurnett R (2021): A study of PDC-1421 treatment in adult patients with attention-deficit hyperactivity disorder (ADHD). ClinicalTrials.gov. ↥
Ilipilla G, Arnold LE (2024): The role of adrenergic neurotransmitter reuptake inhibitors in the ADHD armamentarium. Expert Opin Pharmacother. 2024 Jun;25(8):945-956. doi: 10.1080/14656566.2024.2369197. PMID: 38900676. REVIEW ↥