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Moclobemide for ADHD

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Moclobemide for ADHD

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Moclobemide is a reversible MAO-A and MAO-B inhibitor1 and subsequently inhibits serotonin and norepinephrine metabolism so that serotonin and norepinephrine are broken down more slowly and consequently are available longer.

No diet is required due to reversibility.

Only a very small number of sources on moclobemide in ADHD can be found.

  • PubMed finds only one study under moclobemide and ADHD since 2000 that addresses the treatment of comorbid opiate addiction and ADHD.2
  • Häßler reports good efficacy on the ADHD symptoms of hyperactivity and frustration intolerance.3

High side effects at the beginning.
Tapering off when discontinuing.

Moclobemide is likely to be useful in only a few specific ADHD cases.

  1. Edel, Vollmoeller (2006): Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung bei Erwachsenen, Seite 45 ↥

  2. Vaiva De Lenclave; Bailly (2002): Treatment of comorbid opiate addiction and attention-deficit hyperactivity disorder (residual type) with moclobemide: a case report; Prog Neuropsychopharmacol Biol Psychiatry. 2002 Apr;26(3):609-11. ↥

  3. Häßler (2009): substanzgebundene Alternativen in der Therapie von ADHS, Seite 175, in: Häßler (Hrsg) das ADHS Kaleidoskop – State of the Art und bisher nicht beachtete Aspekte von hoher Relevanz; medizinisch wissenschaftliche Verlagsgesellschaft ↥

Diese Seite wurde am 13.03.2023 zuletzt aktualisiert.
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