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Levophacetoperan for ADHD


Levophacetoperan for ADHD


Other names: NLS-3 or (R, R)-enantiomer of phacetoperane
Brand name: Lidepran® (8228 R.P.)

Levophacetoperan is the reverse ester of methylphenidate.
It was marketed in Canada and Europe in the late 1950s to treat ADHD, obesity, and depression.

(Levo-)phacetoperan differs from other stimulants in its effect on the catecholamine system and showed a favorable benefit-risk ratio.
It has been in extensive clinical use in nearly a thousand children and adolescents. It was found to have fewer side effects than comparable stimulant treatments over wide dose ranges.

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