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Levophacetoperan for ADHD

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Levophacetoperan for ADHD

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Levophacetoperan1

Other names: NLS-3 or (R, R)-enantiomer of phacetoperane
Brand name: Lidepran® (8228 R.P.)

Levophacetoperan is the reverse ester of methylphenidate.
It was marketed in Canada and Europe in the late 1950s to treat ADHD, obesity, and depression.

(Levo-)phacetoperan differs from other stimulants in its effect on the catecholamine system and showed a favorable benefit-risk ratio.
It has been in extensive clinical use in nearly a thousand children and adolescents. It was found to have fewer side effects than comparable stimulant treatments over wide dose ranges.

  1. Konofal E, Lecendreux M, Bizot JC, Lormier AT, Figadere B (2023): NLS-3 (Levophacetoperane or (R,R) Phacetoperane): A Reverse Ester of Methylphenidate: A Literature Review. Curr Med Chem. 2023 Jan 20. doi: 10.2174/0929867330666230120161837. PMID: 36683369. REVIEW ↥

Diese Seite wurde am 13.03.2023 zuletzt aktualisiert.
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